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	<title>Comments on: Acromegaly, size matters</title>
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		<title>By: Growth Hormone (HGH), Generalities and Controversy:: BecomeNatural . com</title>
		<link>http://www.becomenatural.com/blog/2007/04/acromegaly-size-matters/comment-page-1/#comment-922</link>
		<dc:creator>Growth Hormone (HGH), Generalities and Controversy:: BecomeNatural . com</dc:creator>
		<pubDate>Thu, 19 Apr 2007 22:04:23 +0000</pubDate>
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		<description>[...] Growth hormone excess: (acromegaly and pituitary gigantism) [...]</description>
		<content:encoded><![CDATA[<p>[...] Growth hormone excess: (acromegaly and pituitary gigantism) [...]</p>
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		<title>By: Gigantism (giantism), getting bigger :: BecomeNatural . com</title>
		<link>http://www.becomenatural.com/blog/2007/04/acromegaly-size-matters/comment-page-1/#comment-919</link>
		<dc:creator>Gigantism (giantism), getting bigger :: BecomeNatural . com</dc:creator>
		<pubDate>Thu, 19 Apr 2007 21:54:54 +0000</pubDate>
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		<description>[...] Gigantism (from Greek gigas, gigantas &#8220;giant&#8221;) is an excessive secretion of growth hormone or IGF-I (insulin-like growth factor I) during childhood, before the closure of the bone growth plates. This excess growth hormone causes overgrowth of the long bones and very tall stature.  Acromegaly is the same disorder of IGF-I excess when it occurs after the growth-plate cartilage fuses in adulthood. Gigantism is a nonspecific term referring to any standing height more than 2 standard deviations above the mean for the person&#8217;s sex, age, and Tanner stage (ie, height Z score &gt; +2.0). These disorders exist along a spectrum of IGF-I hypersecretion wherein the developmental stage when such excess originates determine the principal manifestations. [...]</description>
		<content:encoded><![CDATA[<p>[...] Gigantism (from Greek gigas, gigantas &#8220;giant&#8221;) is an excessive secretion of growth hormone or IGF-I (insulin-like growth factor I) during childhood, before the closure of the bone growth plates. This excess growth hormone causes overgrowth of the long bones and very tall stature.  Acromegaly is the same disorder of IGF-I excess when it occurs after the growth-plate cartilage fuses in adulthood. Gigantism is a nonspecific term referring to any standing height more than 2 standard deviations above the mean for the person&#8217;s sex, age, and Tanner stage (ie, height Z score &gt; +2.0). These disorders exist along a spectrum of IGF-I hypersecretion wherein the developmental stage when such excess originates determine the principal manifestations. [...]</p>
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